In October 2023, A Research Study to See How Semaglutide Works Compared to Placebo in People with Type 2 Diabetes and Chronic Kidney Disease (FLOW) trial assessing the effect of semaglutide versus placebo on the progression of renal impairment in people with T2DM and chronic kidney disease was stopped prematurely due to results of an interim analysis showing significant efficacy of semaglutide with full results due to be released in the first half of 2024 [39]
In 2022, 40 million people were prescribed semaglutide to treat obesity, diabetes or both
Echocardiography was performed by using an Animal Digital Ultrasound Imaging System (Mylab Sixvet, Saote, Italy) with a 30-MHz scan probe
GLP-1 controls specific types of appetite rather than baseline hunger
Liraglutide attenuates the depressive- and anxiety-like behaviour in the corticosterone induced depression model via improving hippocampal neural plasticity
Stress management, adequate sleep (7-9 hours nightly), and addressing emotional eating patterns are also crucial