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Once the tumour became arrested in the palbociclib-treated group, mice were further randomized to receive either RSL3 (50 mg kg 1 , five times per week for 2 weeks) or the vehicle, resulting in four experimental groups: vehicle, RSL3, palbociclib and palbociclib + RSL3

Reducing oxidative stress may help prevent chronic diseases and promote overall well-being

This phased approach is designed to systematically transition from computational mRNA-based findings to a clinically applicable protein-level diagnostic tool

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Gently swirl or roll the vial until fully dissolved

doi: 10.1073/pnas.1601461113