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Then in May 2025, the first direct head-to-head trial SURMOUNT-5 was published in the New England Journal of Medicine , putting the two medications head-to-head in the same patients, at the same time, under the same conditions

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ISCs are involved in electron transport, substrate binding, enzymatic catalysis and play critical roles in maintaining genomic stability since several DNA polymerases and helicases require interaction with ISCs for proper functioning

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57 In the process in which uric acid is produced, ROS, particularly superoxide anions and hydrogen peroxide (H 2 O 2 ), are generated as byproducts