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PXD029992
231 In cisplatin-resistant bladder cancer, constitutive NF-B activity upregulates EMT and stemness markers, as well as ABCB1, driving resistance and progression
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Oestrogen dependence may be due to the upregulation of the 17-hydroxysteroid dehydrogenase-1 and aromatase genes, whereas progesterone resistance may result from the failure of progesterone receptor activation and transcription of progesterone target genes [99]
Its called your detoxification system
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