Studies show an age-adjusted incidence of 2.4 per 100,000 person-years for males and 9.8 for females [4]
By influencing central nervous system signaling, DSIP is studied for its potential to help organisms maintain balance under physical, emotional, or environmental stress
This is particularly relevant with the recent approval of Rezdiffra (resmetirom, Madrigal Pharmaceuticals), which has both a fibrosis and MASH benefit
Jain P, Bhatla SC (2014) Signaling role of phospholipid hydroperoxide glutathione peroxidase (PHGPX) accompanying sensing of NaCl stress in etiolated sunflower seedling cotyledons
These medications work peripherally on blood vessels
however, delays of approximately nine years from the initial symptom onset remain common [1]