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they should not be self-administered

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We generated chimeric ligand-receptor pairs in which the ligand/receptor interaction domains of Delta and Notch are replaced by the corresponding interaction domains of vertebrate Follicle Stimulating Hormone (FSH) and FSH Receptor (FSHR), and the native Drosophila Notch NRR is replaced by the NRR of either LIN-12 or GLP-1 (Figure 2x)

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