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One consequence is reduced blood circulation in the inner ear
Thus, it can be hypothesized that the critical importance of Ca 2+ signaling in eryptosis is linked to the expulsion of the nucleus and the organelles (primarily mitochondria) in precursors of erythrocytes during erythropoiesis
As diabetes rates continue to rise, the demand for insulin has also increased significantly
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Rare systemic effects have also been observed in experimental models
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