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The best-documented human uses come from pediatric endocrinology
Many researchers say they barely feel their weekly injection after the first few weeks
Uetake et al., 1997
Steady-state exposure typically occurs after 4 to 5 weeks of weekly administration, and disrupting that rhythm slows things down
Subsequently, we further confirmed that endo-IWR1 suppressed the NTAPP-induced nuclear -catenin in hDP cells (Supplementary Figure 4c)
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