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Diabetes, Obesity and Metabolism , 24 (8), 15531564

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15 December 2021

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But an important question often follows early success: what happens long term

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While GLP-1 RAs have provided an important new weapon for those suffering from profound obesity, they unfortunately trigger the same counter-productive mechanisms as other weight-loss efforts, which rely on caloric restriction, resulting in muscle loss, which limits the fat loss and metabolic benefit

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