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Zaletel K, Krhin B, Gaberscek S, Bicek A, Pajic T, Hojker S

showed that PT2385 selectively disrupts the heterodimerization of HIF-2 with ARNT, thereby inhibiting the transcription of downstream oncogenic targets such as VEGF, EPO, and cyclin D1

Collagen is the most abundant protein in the human body, accounting for approximately 30% of the total protein content

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