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[7] Phospholipase C (PLC) may cleave phosphatidylinositol 4,5-bisphosphate (PIP2) into secondary messengers, IP3 and DAG (diacylglycerol)

Who should avoid semaglutide Semaglutide should not be used by people with: Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Personal or family history of medullary thyroid carcinoma (MTC) Serious allergic reactions to semaglutide Be extra careful if you have pancreatic or kidney problems, diabetic retinopathy, or are pregnant or breastfeeding

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