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When one drug inhibits CYP enzymes responsible for metabolising another CNS drug, plasma and brain concentrations may rise, increasing the risk of toxicity
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Dynamic contrast enhanced MRI demonstrated contrast enhancement in the periventricular brain parenchyma (site of infection) in infected mice, which persisted throughout the duration of the scan (20 min)
ATP, Adenosine triphosphate
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Our data further indicate that GSH acts as a rheostat to regulate metabolism, mitochondrial function and ETC activity in B cells
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