about glp 1 Can one drug do it all? Reviewing the expanding clinical universe of GLP-1 agonists Indications for GLP-1/GIP RA Summary

Pfizers push into weight-loss drugs suffers another setback: Novo Nordisk and Eli Lilly are cornering the market as pharma companies struggle to develop an effective weight-loss drug pill

doi:10.4081/aiua.2014.3.164

The choice between the two should be based on individual preferences and medical guidance

stratifying by metabolic status, by genetic risk such as GBA and LRRK2 variants in Parkinsons or APOE in Alzheimers, by disease stage, and potentially by GLP-1R polymorphism is the most plausible route to a positive trial

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These efforts, along with implementing diet and lifestyle changes, will provide the most effective and sustainable outcomes and help inform the decision of whether to use medications or not.