The biological impact of GLP-1RAs on cancer risk operates through multiple mechanistic pathways, including direct effects on tumor cell metabolism and proliferation, modulation of immune responses in the tumor microenvironment, and regulation of inflammatory signaling networks (911)
This tier may also include cases where causation is harder to prove due to limited testing, preexisting conditions, or incomplete medical records
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Gribble, Insulin-like peptide 5 is an orexigenic gastrointestinal hormone
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