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Emulsification Solvent Evaporation (ESV) technique was used to develop NLCs where formulation yield spherical and smooth NLCs with more than 70% entrapment efficiency which were optimized through a BoxBehnken design

Table 3 demonstrates plant-derived bioactive compounds/extracts known for their in vivo anti-hyperthyroidism activity

Studies have shown that overproduction of reactive oxygen and nitrogen species (RONS), including superoxide anion, hydroxyl radical, hydrogen peroxide, and nitrogen oxides, induces chondrocyte oxidative stress, mitochondrial dysfunction, and extracellular matrix degradation, thereby exacerbating OA[10, 11]

Reporting of prescribing and preparation errors were also higher for compounded medications, the paper found

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