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Effect on function: Tamoxifen can temporarily or permanently impact ovarian function, potentially reducing fertility in particular women

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(21) regarding the correlation between hyperinsulinemia and hyperandrogenism, to the foundational work by Dunaif and Nestler (19801990) that established the causal relationship between IR and PCOS (23, 24), and through to the debates on the universality of this axis following the formulation of the Rotterdam diagnostic criteria (2003) (25, 26)

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This is harder on a GLP-1 because the medication suppresses appetite, so protein has to be planned and eaten first at each meal rather than left to chance