And during that year, I did feel flat sometimes
Incidence of pancreatitis and pancreatic cancer in a randomized controlled multicenter trial (SAVOR-TIMI 53) of the dipeptidyl peptidase-4 inhibitor saxagliptin

Trials such as TOPCAT and PARAGON-HF failed to meet hospitalization reduction primary endpoints in patients with HFpEF.(5,6) However, the EMPEROR-Preserved and DELIVER trials led the ACC/AHA/HFSA to recommend the sodium glucose-cotransporter 2 (SGLT2) inhibitors, empagliflozin and dapagliflozin, for hospitalization reduction in HFpEF.(7-9) Semaglutides Role in HFpEF Semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1 RA) enhances glucose-dependent insulin secretion, suppresses inappropriate glucagon release, and slows gastric emptying.(10) GLP-1 RAs, including liraglutide, dulaglutide, and semaglutide significantly improve glycemic control, promote weight loss, and reduce atherosclerotic cardiovascular and renal risk.(11) Among the approved GLP-1 RAs in the United States, semaglutide and tirzepatide, a dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 RA, have emerged as possible therapies for patients with HFpEF.(12-14) These agents may improve physical function and enhance quality of life by reducing adiposity, leptin levels, and RAAS activation

Regarding thyroid safety: animal studies with GLP-1 receptor agonists have identified C-cell tumours in rodents at high doses, but the relevance of these findings to humans is uncertain
8) Polycystic Ovary Syndrome (PCOS) and Fertility: Enhancing Reproductive Health GLP-1 medications are demonstrating efficacy in improving fertility outcomes in women with PCOS, a hormonal disorder characterized by irregular periods, excess androgens, and cysts on the ovaries
00:36:05 Jennifer Clements Do they understand what may happen