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Systematic reviews and meta-analyses of randomised controlled trials suggest that berberine may modestly reduce fasting blood glucose, HbA1c (a marker of long-term glucose control), and post-meal glucose levels in people with type 2 diabetes or non-diabetic hyperglycaemia (prediabetes)

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[16] [17] Any suspected side effects from hydroxocobalamin injections should be reported via the MHRA Yellow Card scheme (available at yellowcard.mhra.gov.uk)

GLP-1 receptor agonists include semaglutide (trade names: Ozempic, Wegovy, Rybelsus)