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Instead, it binds covalently to the selenocysteine active site of GPX4, inactivating the enzyme and triggering lipid ROS accumulation (8284)

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(2) Hillary H Le, Suleyman S Cinaroglu, Elise C Manalo, Aysegul Ors, et al (2021) Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells eBioMedicine, 2021 Oct 21, Volume 73, Page 103646

Log In to Unlock AOD9604 is a modified peptide fragment of human growth hormone, comprising amino acids 176191

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