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3.1.9 Epigallocatechin-3-gallate (EGCG) and epicatechin EGCG, a polyphenol abundant in green tea extract, is a STAT1 inhibitor.EGCG prevents cisplatin cytotoxicity through anti-apoptotic and antioxidant effects ( in vitro and ex vivo (Xie et al., 2004).EGCG acts through phosphatidylinositol 3-kinase (PI3K)/Akt signalling in cochlear NSCs to promote cell growth and neuronal differentiation, which can be used for the treatment of hearing loss (Zhang et al., 2016), and has an important protective mechanism against cochlear oxidative damage

If you are on a lower dose that does not consume a full pen within the usage window, understanding dose scheduling flexibility helps maximize each pen

Bergenstal RM, Wysham C, Macconell L, Malloy J, Walsh B, Yan P, et al

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Fat distribution shifts from hips and thighs (subcutaneous) toward the abdomen (visceral)

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