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Trial data show that stopping a GLP-1 leads to regain of roughly two-thirds of lost weight within a year

Specific POPs have been associated with a higher risk for peripheral neuropathy among those with either impaired fasting glucose or diabetes, beyond the heightened risk due to diabetes itself

Gene sets related to the MAPK and mTOR signaling pathways were retrieved from the Molecular Signatures Database (MSigDB) via the msigdbr R package

It is uniquely high in glycine, proline, and hydroxyproline, which are specific to the "unfolding" of connective tissue repair

If 300 mcg produces grogginess, reduce rather than increase further

If hunger is rising, routines are slipping, and the scale is creeping up for several weeks, that's a signal to check in early