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FDA Approved Weight Loss Medications orlistat (Xenical/Alli) phentermine-topiramate (Qsymia) naltrexone-bupropion (Contrave) liraglutide (Saxenda) semaglutide (Wegovy) setmelanotide (IMCIVREE) Experts explain that the increasing recognition that diet and exercise alone are unlikely to result in sustained weight loss had led to renewed interest in medication to supplement lifestyle changes

But its their weight loss effects that have caused a surge in interest

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For this to translate into a loss of body fat, we will not only have to make the fat available to the cell so that it can use it as a metabolic substrate, but we must also generate a caloric deficit (to gradually lose fat) through nutrition and physical activity

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