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Lixisenatide is cleared by glomerular filtration, followed by tubular reabsorption and subsequent metabolic degradation (126)
This helps control cravings and manage food intake, ultimately contributing to weight loss over time
Is it normal for weight loss on GLP-1 treatment to slow down or plateau
How Much Weight Can You Lose in a Month on a GLP-1 Program
doi:10.1073/pnas.1000138107
Reduced hepatic steatosis changes the hepatic extraction ratio of high-clearance drugs
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