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Without clinical trials, we don't have a clear picture of potential long-term effects, interactions with other medications, or who should avoid it

GLP-1 receptors are expressed in multiple brain regions, including areas involved in arousal, sleep-wake regulation, and energy homeostasis

A B12 injection may be worth discussing if: You have absorption problems: Conditions like Crohn's disease, celiac disease, or atrophic gastritis can reduce how well your body absorbs B12 from food, and past gastric surgery can have a similar effect

Additionally, erastin targets the mitochondrial voltage-dependent anion system (VDAC) (66)

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A key finding associated with SGx shows increased circulating bile acids (BAs) and fibroblast growth factor 19 (FGF19)