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P.WalligM
Lignans from flaxseed, converted to enterolactone (EL) and enterodiol by gut microflora within the intestines, possess weak estrogenic activity that competes with endogenous oestrogens for ER binding causing decreased mitogenic stimulation and lower circulating estrogen concentrations via upregulation of sex hormonebinding globulin (SHBG) (189, 190)
doi:10.1007/s12325-021-01789-5
Do not exceed 250 mcg daily without documented enzyme stability
Scandinavian Journal of Gastroenterology
doi: 10.3389/fmicb.2020.00090 74 HanLShuXWangJ
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