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In the SYNERGY-NASH trial, tirzepatide showed significant rates of MASH resolution, up to 62%, compared to 10% with placebo, and improved fibrosis in over 50% of participants, said Isaacs

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There are no adequate, large studies that show testosterone supplementation is safe in women for maintaining muscle mass

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Furthermore, GH-secretory mechanisms are also impaired in hypothyroidism, not only because a decrease in the hypothalamic content of GHRH [116, 117] but also because SS appears to be increased, at least in the rat [117, 118, 119]

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