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doi: 10.1007/s00134-020-05991-x 234 RushworthG
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- from the @foundmyfitness podcast The youngest age I would consider evaluating if Finasteride (or Dutasteride) is worthwhile
Wu, G., Fang, Y
Advanced molecular studies reveal that FOXO4-DRI promotes p53 nuclear exclusion and subsequent mitochondrial targeting, where p53 interacts with BCL-2 family proteins to promote mitochondrial outer membrane permeabilization and cytochrome c release
How it works: G-actin sequestration: TB-500 binds G-actin in a 1:1 complex, maintaining a pool of monomeric actin that cells can quickly mobilize for cytoskeletal remodeling and migration toward injury sites (structural basis confirmed in PMC517612)
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