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GPX might neutralize their toxic action and compensate in some way the loss of defense capability against oxygen radicals [2]

Silwal, P

Also, salvianolic acid B pretreatment induces Nrf2 and phase II enzymes by activating phosphoinositide 3-kinase (PI3K) and protein kinase C (PKC) pathways, thereby preventing acetaminophen-induced hepatotoxicity in mice (Lin et al., 2015)

The Neh1 domain contains a bZIP binding motif responsible for the formation of a heterodimer with small musculoaponeurotic fibrosarcoma (sMaf) proteins and mediates the binding to ARE sequences, within the promoter of NRF2 target genes [152]

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194 PRMT7 can promote the transcription of Oct4, c-Myc, Nanog, and Klf4 by regulating the histone methylation of miR-24-2 and miR-221 promoters and inhibiting the expression of miRNA