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Clinical outcomes: In the STEP 1 clinical trial, participants using semaglutide 2.4 mg (Wegovy) lost an average of 14.9% of their body weight over 68 weeks, compared to 2.4% in the placebo group
Kumar A U, A
Metformin's insulin-sensitizing effects may enhance tirzepatide's glucose-dependent actions, while tirzepatide's potent appetite suppression and gastric effects add to metformin's modest weight benefits
Early results show weight loss of up to 11 pounds in 30 days, 17 pounds in 60 all at a fraction of conventional doses
