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Clinical guidelines suggest that a weight loss of 5% to 10% of body weight can lead to important health benefits, such as lower blood pressure, improved blood sugar control, and better cholesterol levels
Adequate hydration is critical, though fluid needs should be individualized based on activity level, climate, and medical conditions (patients with kidney disease or heart failure should follow their provider's fluid recommendations)
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Cell Metab 33(7):14661482 Hao Z et al (2014) Vagal innervation of intestine contributes to weight loss after Roux-en-Y gastric bypass surgery in rats
These could be signs of an infection (Zhu, 2019)