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Upon receptor binding, IGF1R undergoes autophosphorylation, initiating downstream signaling pathways, including: Phosphoinositide 3-kinase (PI3K)/Akt pathway Mitogen-activated protein kinase (MAPK) pathway These pathways are associated with intracellular signal transduction processes, including regulation of gene expression, protein translation, and cellular signaling dynamics at the molecular level

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The detection limit was 15.9 nmol/l (2.8 g/l) and the assay was linear between 45 and 8041 nmol/l (8 and 1417 g/l)

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