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Tolerability and Safety Questions Both candidates are likely to be judged partly on gastrointestinal tolerability: nausea, vomiting, diarrhea, constipation, dose escalation, and discontinuation due to adverse events

Complex carbohydrates provide sustained energy, fiber, and important B vitamins

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Week 36: Appetite Suppression Deepens and Cravings Decline By weeks 3 through 6, most patients experience substantial appetite reduction and decreased food cravings, particularly for high-calorie or processed foods

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Participants who received a placebo achieved a 2.6% weight loss from baseline