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FDA Position on Compounded GLP-1 Products The Food and Drug Administration has expressed serious concerns about unapproved GLP-1 medications used for weight loss

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Unlike semaglutide and tirzepatide (which could be compounded during shortages), retatrutide has never been FDA-approved

Government action adding additional pricing uncertainty As new drugs and indications reshape the clinical landscape, policymakers are reshaping cost and coverage frameworks

Compounded semaglutide, including formulations with glycine, is prepared by licensed compounding pharmacies under different regulatory frameworks

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