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Consider stool softeners or osmotic laxatives if needed, and consult your prescriber before starting stimulant laxatives regularly

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In animal cells the fate of ITCs is well characterized: conjugation to glutathione by GSTs resulting in its intracellular depletion and subsequent degradation of dithiocarbamates through enzymatic events catalysed by -glutamyltranspeptidase, cysteinylglycinase and N -acetyltransferase via the mercapturic acid pathway 76

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Step 2: Hydroxyethylation Reaction Purified 2-methyl-5-nitroimidazole is dissolved in alkaline ethanol solution, followed by addition of ethylene oxide as the hydroxyethylation reagent under constant-temperature stirring