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A notable upregulated protein in dementia compared with CN was glutathione synthetase (GSS) (1.7-fold, p = 0.02)
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Retinoid mechanisms differ fundamentally from GHK-Cu by directly binding nuclear receptors controlling gene expression and cell turnover rather than providing enzymatic cofactors supporting natural processes, creating stronger effects but also more pronounced dependency where discontinuation often triggers rebound effects
B12 injections, on the other hand, allow up to 100% absorption and immediate use by the body
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