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The entire process is fully aseptic and takes place inside an ISO Class 5 environment at our U.S
Reason 2: Mechanistic symmetry between the two pathways
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It represents a precautionary approach given limited long-term data rather than a response to documented concerns
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Yeast mitochondrial NAD(+)-dependent isocitrate dehydrogenase is an RNA-binding protein [PMID: 7505425] Laboratory literature summary: Yeast mitochondrial NAD(+)-dependent isocitrate dehydrogenase is an RNA-binding protein
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