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Our Approach to Holding Drug Companies Responsible On October 6, 2023, Siskinds LLP filed a proposed GLP-1 drug class action in the Supreme Court of British Columbia against Novo Nordisk and affiliated entities on behalf of persons in Canada who were prescribed and used Ozempic, Rybelsus, and/or Wegovy and suffered serious injuries
These drugs exhibit anti-inflammatory and immunoregulatory properties while promoting cell autophagy and phagosome maturation by inhibiting the mammalian target of the rapamycin (mTOR) signaling pathway [8]
The equivalent injectable dose would therefore be approximately 2mg to 2.4mg weekly, since injectable bioavailability approaches 100%
In cases of chronic gastrointestinal conditions, I recommend sublingual tablets or liquid drops to bypass the gut
If nausea persists beyond two weeks at a stable dose, discuss it with your prescriber before attributing it to caffeine alone