In this review, we review the evidence supporting combined SGLT2i and GLP-1RA therapy in type 2 diabetes with a focus on cardiometabolic outcomes, and we propose a pragmatic framework for clinical use
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doi: 10.1097/01.AOG.0000231688.08263.47 8 ZinmanBWannerCLachinJMFitchettDBluhmkiEHantelSet al
Lancet 392:15191529 Gerstein HC, Colhoun HM, Dagenais GR, Diaz R, Lakshmanan M, Pais P, Probstfield J, Riesmeyer JS, Riddle MC, Rydn L, Xavier D, Atisso CM, Dyal L, Hall S, Rao-Melacini P, Wong G, Avezum A, Basile J, Chung N, Conget I, Cushman WC, Franek E, Hancu N, Hanefeld M, Holt S, Jansky P, Keltai M, Lanas F, Leiter LA, Lopez-Jaramillo P, Cardona Munoz EG, Pirags V, Pogosova N, Raubenheimer PJ, Shaw JE, Sheu WH, Temelkova-Kurktschiev T (2019) REWIND Investigators