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Endogenous GLP-1 is rapidly degraded by the enzyme Dipeptidyl Peptidase-4 (DPP-4) , with an effective plasma half-life of only ~2 minutes after intravenous injection ( [39] ) ( [40] )
2025 Dec;222:108045
Semaglutide is a GLP-1 receptor agonist (glucagon-like peptide-1 receptor agonist) that helps regulate blood sugar levels
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