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Many Californians using GLP-1 medications are hearing about maintenance doses, micro-dosing, and tapering plans but arent sure how they work or whether theyre necessary
A Lilly-funded head-to-head study published in 2025 showed Zepbound delivering stronger weight-loss outcomes than Novo's Wegovy, including greater waist reduction and a higher likelihood of patients losing at least 25% of their body weight over 72 weeks
The resulting products are not FDA-approved
Among these benefits, one stands out for long-term health: lowering LDL cholesterol , the so-called bad cholesterol that plays a central role in heart disease
Regardless, talk to your doctor about how long you should stay on semaglutide
If you have a strong medical reason, your provider may discuss alternatives
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