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It should be noted, however, that the radioligands used in these SPECT studies are affected by SSRIs, and are not as specific and sensitive as the current [ 11 C]PE2I PET ligand [38]
Johansen and colleagues (1999) reported that ipamorelin administration was associated with dose-dependent longitudinal bone growth in rats over a 15-day study, an effect the authors attributed to downstream GH-mediated action rather than a direct skeletal mechanism [4]
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