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In the first step holocarboxylase synthetase generates a biotin-AMP intermediate and in the second step the activated biotin is transferred to the carboxylase enzyme with release of AMP
doi: 10.18999/nagjms.83.2.343
Since these drugs are intended to be used long-term, this price difference could equate to thousands of dollars throughout treatment
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16(1): e52564
Tatsumi, R
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