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One side effect that gets people asking questions: dysesthesia TRIUMPH4 reporting mentions dysesthesia (odd, uncomfortable sensations like tingling/burning) and says it was generally mild and infrequently led to discontinuation

Moreover, the Summary of Product Characteristics on the Electronic Medicines Compendium states that Therapeutic experience in patients 75 years of age is limited

And research suggests that when its paired with calcium, the effect can be even better (3)

Ultrasound guidance is necessary when performing these injections

When using cooling packs, position them carefully to avoid direct contact with the medication, as this can cause freezing, which is just as harmful as overheating

So if everyday movement is painful or irritating, weight loss can give your joints a break, increase your mobility, and lower the risk of developing conditions like osteoarthritis