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These mice also showed colonic inflammation linked to gut microbiota dysregulation and PSRC1 deficiency increased liver flavin monooxygenase 3 (FMO3) expression, while PSRC1 overexpression suppressed FMO3 (112)

It does not establish that two peptides used together are safer or more effective than either one alone

Unlike the C-terminal amide of Melanotan II, the free carboxylate is titratable and carries an additional negative charge at neutral pH, so record buffer composition and pH alongside concentration if the two molecules are being compared in the same assay

In contrast, ghrelin, which is secreted from gastric epsilon cells, promotes hunger

Medvidovic-Grubisic et al., 2017

Psychiatry 22, 120126