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(August 2001)
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The well-known geriatrician-haematologist Larry Solomon, working at Yale University in the USA, wrote 20 years ago: if I had treated only those people who actually had too low serum B12 and elevated MMA values, then I would not have treated approximately two-thirds of the people with a favourable response to B12 supplementation (note: partly via injections, partly via oral supplementation)
This determination was based on chronic toxicity studies, genotoxicity studies, and human clinical trial safety data
The formulations also were posited to be impactful when tested alongside agents that may be associated with alopecia
The result can be low potassium, or hypokalaemia, in the first days of treatment
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