These studies, ranging from 1.5 to 4 years, show that semaglutide remains safe and effective to take long-term
Some studies report stable or slightly improved bone density with GLP-1 therapy, while others suggest potential decreases, particularly in the context of significant weight loss
In another randomized double blind study, three-month acetyl-l-carnitine supplementation provided statistically significant support for mental function, including memory and attention, compared to placebo
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Paracetamol (maximum 4 g daily) is a safe first-line option for most patients, whilst ibuprofen (maximum 1.2 g daily for over-the-counter use) may be used if paracetamol proves insufficient, provided you have no contraindications such as kidney disease or gastric ulcer history
4.6.2 Retinal disease Diabetic retinopathy (DR) is the most prevalent microvascular complication of diabetes and the leading cause of preventable blindness among working-age individuals (81)