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5.3 Exercise regulates exerkines expression Exerkines are bioactive molecules secreted by exercise-stimulated tissues such as skeletal muscle, adipose tissue, liver, brain, and other organs, including myokines, cardiokines, hepatokines, adipokines, neurokines, lactate, and miRNAs
In a 2022 blog post, Volkow emphasized the need for a pragmatic approach to addiction treatment, stating, the perfect should not be the enemy of the good. She highlighted that only 13% of individuals with drug use disorders receive any treatment, advocating for reduced substance use, not just complete abstinence
dysfunctions of intracellular signaling networks, e.g., p53, nuclear factor-B, and Janus kinases
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