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In addition, the expression of BDNF, 5HT 1A , GABA-T, and GAD was decreased, and the expression of GluR 2 and 5HT 2A was increased in the hippocampus of insomnia rats, and these parameters showed a regulatory trend in a doseresponse relationship after senegenin intervention

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The in vitro results support a direct action of GHRP-2 and ghrelin on immune cells, further highlighting their therapeutic potential for inflammatory diseases [2]

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