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Recently, GLP-1 was shown to act on GLP-1R and exert its neuroprotective effects by promoting PTEN-induced kinase 1/Parkin-mediated mitochondrial autophagy and attenuating OS (Wang Y
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The drug has been found to be effective in weight-loss, improved insulin sensitivity and, when combined with exercise and proper diet, can lead to significant and long-lasting weight loss
On the basis of novel data and hypothesis on the possible role of scarce glutathione (GSH) levels in the exacerbation of COVID-19 and of the GSH depleting activity of PAC, this commentary raises the question of whether PAC may be the better choice
*Correspondence: Dongmei Shi, [email protected]
Temporarily reducing fibre and fat intake may help, focusing on plain foods like rice, toast, and bananas until symptoms improve
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