Preclinical studies demonstrated that AOD-9604 was generally safe after chronic oral application in rats and cynomolgus monkeys, with no genotoxic concerns identified
How can B12 deficiency be treated
However, deficiency is common, especially in people with low stomach acid, digestive conditions, vegan or vegetarian diets, or age-related absorption decline
The implications of these changes for human health remain unclear, but it is an active research area
The 2025 NEJM trial comparing tirzepatide directly against semaglutide showed 20.2% versus 13.7% weight loss over the same treatment period
We source our B12 from reputable medical suppliers, so you receive a pure, sterile product held to pharmaceutical standards rather than a supplement of unknown origin